Biochemistry of Drug Resistance

Biochemistry of Drug Resistance provides a comprehensive overview of the biochemical and molecular foundations that drive resistance to therapeutic agents across a range of diseases. The book explores how genetic mutations, altered enzymatic activity, efflux pumps, and metabolic pathway adaptations lead to treatment failures in cancer, bacterial infections, and viral diseases.

Written for researchers, healthcare professionals, and students in pharmacology, molecular biology, and medical sciences, this book bridges the gap between laboratory research and clinical challenges. It delves into mechanisms like multidrug resistance (MDR), epigenetic modifications, and biomolecular signaling pathways involved in therapy resistance.

The content is supported with recent case studies, molecular diagrams, and references to emerging strategies to overcome resistance, such as combination therapies and targeted drug development. This resource is ideal for those seeking to understand resistance mechanisms and develop innovative interventions in modern medicine.